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FLASH GENE
Symbol GPR110 contributors: - updated : 26-03-2007
HGNC name G protein-coupled receptor 110
HGNC id 18990
Location 6p21.1      Physical location : 46.967.813 - 47.010.082
Synonym symbol(s) hGPCR36, PGR19, KPG_012, FLJ22684, FLJ30646, MGC125952
DNA
TYPE functioning gene
STRUCTURE 42.00 kb     16 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status confirmed
RNA
TRANSCRIPTS type messenger
text
  • three new variants (Bjarnadóttir et al, 2006), coding for non-fonctional products
  • identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - splicing 3095 101 911 - -
  • product containing 15 exons
  • lacking exon 8
  • coding for the longest product
  • - splicing 1437 24 218 - -
  • transcript containing 8 exons
  • lacking exons 9 to 16
  • coding for the shortest product
  • - splicing - - - - Bjarnadóttir
  • coding for a non-fonctional product
  • - splicing - - - - Bjarnadóttir
  • coding for a non-fonctional product
  • - splicing - - - - Bjarnadóttir
  • coding for a non-fonctional product
  • EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveesophagus   moderately
     mouth   highly
     pharynx   moderately
    Reproductivefemale systembreastmammary gland lowly
     male systemprostate  lowly
    Respiratorylung   lowly
     respiratory tracttrachea  highly
    Urinarykidney   moderately
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Respiratoryepithelial cell
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a GPS domain
  • a SEA domain
  • a seven transmembrane domain (7tm_2)
  • HOMOLOGY
    interspecies homolog to chimpanzee GPR110 (98.44 pc)
    Homologene
    FAMILY
  • G-protein coupled receptor 2 family
  • LN-TM7 subfamily
  • CATEGORY receptor membrane G
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION may be involved in neuropeptide signaling pathway
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS