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FLASH GENE
Symbol COQ4 contributors: mct/npt - updated : 26-02-2015
HGNC name coenzyme Q4 homolog (S. cerevisiae)
HGNC id 19693
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a predicted N-terminal mitochondrial targeting sequence
    • HOMOLOGY
    interspecies ortholog to yeast Coq4
    Homologene
    FAMILY
  • COQ4 family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,inner
    intracellular,cytoplasm,organelle,membrane
    intracellular,nucleus
    text
  • associated with the mitochondrial inner membrane on the matrix side
    • basic FUNCTION
  • involved in coenzyme q biosynthesis
  • may be a core component of multisubunit complex required for CoQ biosynthesis
  • potentially playing a structural role crucial in the stabilization of a multiheteromeric complex including several, if not all, of the CoQ biosynthetic enzymes
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) COQ10D7
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS