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FLASH GENE
Symbol COQ4 contributors: mct/npt - updated : 26-02-2015
HGNC name coenzyme Q4 homolog (S. cerevisiae)
HGNC id 19693
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Endocrineneuroendocrinepituitary  highly
Nervousbrain    
Reproductivefemale systemuteruscervix highly
Respiratoryrespiratory tracttrachea  highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectivebone  highly
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal
Text fetal eye
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a predicted N-terminal mitochondrial targeting sequence
    • HOMOLOGY
    interspecies ortholog to yeast Coq4
    Homologene
    FAMILY
  • COQ4 family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,inner
    intracellular,cytoplasm,organelle,membrane
    intracellular,nucleus
    text
  • associated with the mitochondrial inner membrane on the matrix side
    • basic FUNCTION
  • involved in coenzyme q biosynthesis
  • may be a core component of multisubunit complex required for CoQ biosynthesis
  • potentially playing a structural role crucial in the stabilization of a multiheteromeric complex including several, if not all, of the CoQ biosynthetic enzymes
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) COQ10D7
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS