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FLASH GENE

Symbol

CLEC1A

contributors: mct - updated : 31-03-2008

HGNC name	C-type lectin domain family 1, member A
HGNC id	24355

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
STRUCTURE	28.00 kb     6 Exon(s)

MAPPING

cloned

Y

linked

N

status

provisional

regionally located

located near the natural killer cell gene complex

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed variant 1 6 - 1791 - 280 - Ebner (2003)

EXPRESSION

Type

widely

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive esophagus       highly Endocrine neuroendocrine pituitary     highly Hearing/Equilibrium ear       highly Nervous ganglia sensory ganglia dorsal root

cell lineage

cell lines

fluid/secretion

at STAGE

physiological period

pregnancy

Text

placenta

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	a single carbohydrate recognition domain (CRD) with 6 conserved and 2 additional cysteine residues
	a cytoplasmic putative immunoreceptor tyrosine-based motif (YSST) and several potential phosphorylation sites

HOMOLOGY

Homologene

FAMILY

C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily.

CATEGORY

adhesion , signaling

SUBCELLULAR LOCALIZATION	plasma membrane
	intracellular
	intracellular,cytoplasm
	intracellular,nuclear envelope

basic FUNCTION

playing a role in regulating dendritic cell function

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS