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FLASH GENE

Symbol

GEMIN7

contributors: - updated : 06-07-2005

HGNC name	gem (nuclear organelle) associated protein 7
HGNC id	20045

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

Homologene

FAMILY

CATEGORY

RNA associated

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm
	intracellular,nucleus,nucleoplasm,nuclear bodies,coiled bodies (Cajal)

basic FUNCTION	playing a role in the cytoplasmic assembly of small nuclear ribonucleoproteins (sn RNPs)
	playing a role in pre m-RNA splicing
	playing a role in the assembly of transcriptosomes

CELLULAR PROCESS

nucleotide, RNA splicing

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component	component of the SMN complex
	spliceosomal subunit

INTERACTION

DNA

RNA

small molecule

protein	interacting with several Sm proteins of the spliceosomal Sn RNPs
	directly with SMN1 and GEMIN6 and mediating the association of GEMIN6 with the SMN complex

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS