Symbol
| LYRM4
| contributors: mct/npt/pgu - updated : 09-05-2014
|
HGNC name
| LYR motif containing 4
|
HGNC id
| 21365
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
constitutional
|  
|  
| --low
|  
|
in FRDA patient cells | constitutional
|  
|  
|  
| loss of function
|
disrupts normal mitochondrial and cytosolic iron homeostasis | |
Variant & Polymorphism
|
| |
Candidate gene
Marker
Therapy target
| | | |
| Lyrm4 was down-regulated in the prefrontal cortex of mice with microdeletions in the locus syntenic to 22q11.2 patients affected by schizophrenia |