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FLASH GENE
Symbol HAUS4 contributors: mct/npt - updated : 23-04-2020
HGNC name HAUS augmin-like complex, subunit 4
HGNC id 20163
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
  • augmin family
    • CATEGORY DNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic
    intracellular,cytoplasm,cytoskeleton,microtubule,centrosome
    intracellular,cytoplasm,cytoskeleton,microtubule,mitotic spindle
    basic FUNCTION
  • part of conserved multisubunit protein complex that regulates centrosome and spindle integrity (Lawo 2009)
  • plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis (Uehara 2009)
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • augmin complex (HAUS) is a critical and evolutionary conserved multisubunit protein complex that regulates centrosome and spindle integrity (Lawo 2009)
  • holo-complex HAUS4 and HAUS1 are likely to be directly connected and together interact with HAUS8/HAUS6 (433–955) independent of other subunits
    • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS