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FLASH GENE
Symbol GATA6 contributors: mct - updated : 26-11-2014
HGNC name GATA binding protein 6
HGNC id 4174
ANIMAL & CELL MODELS
  • regulating HNF, required for differentiation of visceral endoderm in mouse embryo
  • Gata6(+/-)Gata5(+/-) mutant embryos have double outlet right ventricles (DORV) associated with subaortic VSDs
  • simultaneous deletion of both murine Gata4 and Gata6 in the pancreas caused severe pancreatic agenesis due to disruption of pancreatic progenitor cell proliferation, defects in branching morphogenesis