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FLASH GENE
Symbol ILVBL contributors: - updated : 05-07-2006
HGNC name ilvB (bacterial acetolactate synthase)-like
HGNC id 6041
Location 19p13.1      Physical location : 15.225.786 - 15.236.577
Synonym name acetolactate synthase homolog
Synonym symbol(s) 209L8, ACTLS, AHAS, AASSL1
DNA
TYPE functioning gene
STRUCTURE 10.00 kb     16 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status confirmed
Map pter - DHPS - TYK2 - D19S221 - ILVBL - CD97 - D19S226 - cen
Authors Gene Map(98),LDB (99)
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 2328 - 632 - Joutel
- - 983 - 224 - Joutel
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   highly
Digestiveintestinelarge intestinecolon highly
Endocrinepancreas   highly
 parathyroid   highly
Lymphoid/Immunelymph node   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • thiamine pyrophosphate enzyme C terminal
  • TPP binding domain
  • HOMOLOGY
    interspecies homolog to murine Ilvb1
    Homologene
    FAMILY TPP enzyme family
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
    basic FUNCTION
  • thiamin pyrophosphate-binding enzyme, putatively involved in the branched chain aminoacid biosynthetic pathway
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    branched chain aminoacid biosynthetic pathway
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    binds 1 magnesium ion per subunit
    protein binds 1 thiamine pyrophosphate per subunit
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS