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FLASH GENE
Symbol DHX40 contributors: SGE/npt - updated : 26-03-2010
HGNC name DEAH (Asp-Glu-Ala-His) box polypeptide 40
HGNC id 18018
Location 17q23.1      Physical location : 57.642.885 - 57.685.712
Synonym name
  • probable ATP-dependent RNA helicase DHX40
  • DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 40 (RNA helicase)
  • protein PAD
  • Synonym symbol(s) PAD, DDX40, ARG147, FLJ22060, FLJ34015, AF319521
    EC.number 3.6.1.-
    DNA
    TYPE functioning gene
    STRUCTURE 42.82 kb     18 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    18 - 3682 - 779 - Xu (2002)
  • isoform 1
  • - - 3451 - 702 - Xu (2002)
  • isoform 2
  • EXPRESSION
    Type ubiquitous
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • one helicase ATP-binding domain
  • one helicase C-terminal domain
  • HOMOLOGY
    interspecies homolog to murine Dhx40 (97.3pc)
    homolog to rattus Dhx40 (97.3pc)
    Homologene
    FAMILY
  • DEAD box helicase family
  • DEAH subfamily
  • CATEGORY enzyme , regulatory , RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • probable ATP-dependent RNA helicase
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule nucleotide,
  • ATP binding
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS