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FLASH GENE
Symbol DYNLRB2 contributors: - updated : 21-02-2006
HGNC name dynein, light chain, roadblock-type 2
HGNC id 15467
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies ortholog to murine Dncl2b
homolog to rattus Rn.27744
homolog to Xenopus Xl.6973
Homologene
FAMILY GAMAD family
CATEGORY motor/contractile
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,cytoskeleton,microtubule
basic FUNCTION
  • involved in microtubule-based movement
  • involved in assembly and motor function of dynein
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component dynein light chain
    INTERACTION
    DNA
    RNA
    small molecule
    protein binding with BMF and BCL2L11
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --low  
    in hepatocellular carcinoma
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS