| basic FUNCTION
| implicated in the levels of dolichol-oligosaccharide intermediate biosynthesis |
|
biosynthetic precursor for dolichol which plays an important role as a sugar-carrier lipid in the biosynthesis of glycoprotein in eukaryotic cells |
|
essential enzyme for dolichol synthesis, permitting global N-linked glycosylation  |
|
key protein for the generation and continuous renewal of photoreceptor outer segments |
|
connects the upstream mevalonate pathway to the membrane-bound N-linked glycosylation machinery supported by a multitude of enzymes and cofactors |
|
key enzyme in the pathway of dolichol, which plays an important role in N-glycosylation of many glycoproteins, including rhodopsin |
|
is an eukaryotic cis prenyltransferase (cis-PT) that catalyzes chain elongation of farnesyl diphosphate via multiple condensations with isopentenyl diphosphate to form dehydrodolichyl diphosphate, a precursor for the glycosyl carrier dolichylpyrophophate involved in N-linked glycosylation |
