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FLASH GENE

Symbol

GPR19

contributors: - updated : 05-07-2006

HGNC name	G protein-coupled receptor 19
HGNC id	4473

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

EXPRESSION

Type	restricted

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Endocrine adrenal gland         Hearing/Equilibrium ear         Lymphoid/Immune lymph node         Nervous brain basal nuclei caudate nucleus     nervous brain basal nuclei putamen     Nervous brain diencephalon thalamus     Reproductive male system testis

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

seven transmembrane segments (7TM) receptor

HOMOLOGY

intraspecies

homolog to D2 dopamine and adregenic receptors,strongly

Homologene

FAMILY

G protein coupled receptor family

CATEGORY

receptor

SUBCELLULAR LOCALIZATION

plasma membrane

basic FUNCTION

may be target of genetic alterations found in several cancers

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral   deletion     in childhood acute lymphoblastic leukemia (ALL)

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS