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	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

NUS1

contributors: mct - updated : 18-06-2018

HGNC name	nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)
HGNC id	21042

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

MRD55 , CDG1AA

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in breast cancer cells

Susceptibility

to Developmental and epileptic encephalopathy (DEE)

Variant & Polymorphism other	NUS1 microdeletions are associated with DEE

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer digestive liver targeting NUS1 in combination with chemotherapeutic drugs, such as 5-FU, could improve the efficacy of current anticancer treatments

ANIMAL & CELL MODELS