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FLASH GENE
Symbol OTUD7A contributors: mct/npt - updated : 15-11-2022
HGNC name OTU domain containing 7A
HGNC id 20718
ANIMAL & CELL MODELS
  • Otud7a KO mice have deficits in cortical neuron dendritic spine density and glutamatergic transmission
  • Otud7a-null mice show reduced body weight, developmental delay, abnormal electroencephalography patterns and seizures, reduced ultrasonic vocalizations, decreased grip strength, impaired motor learning/motor coordination, and reduced acoustic startle (
  • Otud7a-null mice showed decreased dendritic spine density as well as reduced frequency of miniature excitatory postsynaptic currents