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FLASH GENE
Symbol ASB18 contributors: npt/ - updated : 19-09-2006
HGNC name ankyrin repeat and SOCS box-containing 18
HGNC id 19770
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • N terminal ankyrin (ANK) repeats
  • a conserved C-terminal SOCS box motif
    • HOMOLOGY
    Homologene
    FAMILY
  • ankyrin repeat and SOCS box-containing (ASB) family of proteins
    • CATEGORY regulatory , signaling
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic
    CELLULAR PROCESS protein, post translation, targeting
    protein, degradation
    protein, ubiquitin dependent proteolysis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction
    intracellular signaling cascade
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • JAK kinases
  • activated cytokine receptors
  • elonguin B/C complex
    • cell & other
    REGULATION
    induced by cytokines
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS