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FLASH GENE

Symbol

ASB18

contributors: npt/ - updated : 19-09-2006

HGNC name	ankyrin repeat and SOCS box-containing 18
HGNC id	19770

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
STRUCTURE	69.47 kb     6 Exon(s)

MAPPING

cloned

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed ASB18 6 - 1401 50.7 466 - -

EXPRESSION

Type

constitutive of

expressed in	(based on citations)
organ(s)

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	N terminal ankyrin (ANK) repeats
	a conserved C-terminal SOCS box motif

HOMOLOGY

Homologene

FAMILY

ankyrin repeat and SOCS box-containing (ASB) family of proteins

CATEGORY

regulatory , signaling

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,cytosolic

CELLULAR PROCESS	protein, post translation, targeting
	protein, degradation
	protein, ubiquitin dependent proteolysis

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

signal transduction

intracellular signaling cascade

a component

INTERACTION

DNA

RNA

small molecule

protein	JAK kinases
	activated cytokine receptors
	elonguin B/C complex

cell & other

REGULATION

induced by

cytokines

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS