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FLASH GENE
Symbol PTPRH contributors: - updated : 30-06-2006
HGNC name protein tyrosine phosphatase, receptor type, H
HGNC id 9672
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   lowly
Digestiveliver    
 stomach    
Lymphoid/Immunespleen   highly
Nervousbrain    
Respiratoryrespiratory tracttrachea  highly
Urinarybladder   highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • 8 fibronectin type III-like repeats in the extracellular domain
  • protein tyrosine phosphase catalytic domain
  • 25AA signal peptide
    • HOMOLOGY
    Homologene
    FAMILY protein tyrosine phosphatase (PTP) family
    CATEGORY protooncogene
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --low  
    in pancreatic and colorectal cancer
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS