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FLASH GENE
Symbol PTPRH contributors: - updated : 30-06-2006
HGNC name protein tyrosine phosphatase, receptor type, H
HGNC id 9672
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   lowly
Digestiveliver    
 stomach    
Lymphoid/Immunespleen   highly
Nervousbrain    
Respiratoryrespiratory tracttrachea  highly
Urinarybladder   highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • 8 fibronectin type III-like repeats in the extracellular domain
  • protein tyrosine phosphase catalytic domain
  • 25AA signal peptide
    • HOMOLOGY
    Homologene
    FAMILY protein tyrosine phosphatase (PTP) family
    CATEGORY protooncogene
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --low  
    in pancreatic and colorectal cancer
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS