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FLASH GENE

Symbol

PSMD5

contributors: npt - updated : 09-11-2009

HGNC name	proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
HGNC id	9563

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
STRUCTURE	26.87 kb     10 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_005047 10 - 3411 NP_005038 - 504 - -

EXPRESSION

Type

widely

constitutive of

expressed in	(based on citations)
organ(s)

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Blood / Hematopoietic bone marrow       Muscular striatum skeletal

cells

System Cell Pubmed Species Stage Rna symbol Lymphoid/Immune lymphocyte

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

rich in dileucine repeats

HOMOLOGY

Homologene

FAMILY

proteasome subunit S5b family

CATEGORY

regulatory

SUBCELLULAR LOCALIZATION

basic FUNCTION

required for ubiquitin-dependent proteolysis

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS