Symbol
| ARL6
| contributors: shn/mct - updated : 15-12-2020
|
HGNC name
| ADP-ribosylation factor-like 6
|
HGNC id
| 13210
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
|  
|  
|  
| gain of function
|
is significantly up regulated in cilia-dependent RMS cells and tissues | |
Variant & Polymorphism
|
| |
Candidate gene
Marker
Therapy target
| | | |
| oligonucleotide knockdown in zebrafish results in the cardinal features of BBS in zebrafish, including defects to the ciliated Kupffer's Vesicle and delayed retrograde melanosome transpor | |
Bbs3L-null mouse presents disruption of the normal photoreceptor architecture |