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FLASH GENE

Symbol

G6PC2

contributors: mct - updated : 07-03-2011

HGNC name	glucose-6-phosphatase, catalytic, 2
HGNC id	28906

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

to type 2 diabetes to variation of fasting glucose concentrations

Variant & Polymorphism SNP	SNPs from G6PC2 associated with type 2 diabetes (G6PC2 genetic variants were associated to both first- and second-phases insulin secretion)
	significant association between the SNP rs563694 and fasting glucose concentrations

Candidate gene	G6PC2 inhibitors may be an attractive new approach for the treatment of insulin secretion defects in type 2 diabetes
Marker
Therapy target

ANIMAL & CELL MODELS