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	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

TBK1

contributors: mct/npt - updated : 26-10-2018

HGNC name	TANK-binding kinase 1
HGNC id	11584

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

FTDALS4

Susceptibility

to amyotrophic lateral sclerosis

Variant & Polymorphism other	TBK1 variants associated to ALS

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

	TBK1 could be involved in the insulin resistance mechanism related with IR Ser994 phosphorylation in a genetic model of diabetes