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FLASH GENE

Symbol

ZNF317

contributors: npt - updated : 16-04-2009

HGNC name	zinc finger protein 317
HGNC id	13507

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	19p13.2      Physical location : 9.251.055 - 9.274.090
Synonym name	KRAB-containing zinc finger protein 317
Synonym symbol(s)	KIAA1588

DNA

TYPE	functioning gene
STRUCTURE	23.00 kb     7 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed ZNF317-1 - - 3982 - 563 ubiquitous Takashima ZNF317-2 - splicing 4078 67.9 595 ubiquitous Takashima ZNF317-3 - splicing 2214 - 478 lymphocytes,spleen,lung Takashima ZNF317-4 - splicing 2312 - 510 lymphocytes,spleen,lung Takashima

EXPRESSION

Type	ubiquitous

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol blood / hematopoietic erythroid

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Blood / Hematopoietic

cells

System Cell Pubmed Species Stage Rna symbol Blood/Hematopoietic erythroid

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	a KRAB domain
	Krüppel-associated box at the N terminus
	thirteen tandemly arranged zinc finger motifs of the C2H2 type at the C terminus

conjugated

MetalloP

HOMOLOGY

Homologene

FAMILY

krueppel C2H2-type zinc-finger protein family

CATEGORY

regulatory , transcription factor

SUBCELLULAR LOCALIZATION

basic FUNCTION	potential role in erythroid maturation and lymphoid proliferation
	regulation of transcription

CELLULAR PROCESS	nucleotide, transcription, regulation
	cell organization/biogenesis

PHYSIOLOGICAL PROCESS

development

text	hematopoiesis

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

binding

RNA

small molecule	metal binding,
	Zn2+

protein

cell & other

REGULATION

Other

reduced in response to mitogenic stimulation

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS