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FLASH GENE
Symbol MYCNOS contributors: npt - updated : 29-04-2003
HGNC name v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) opposite strand
HGNC id 16911
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines tumor cell lines containing amplified N-myc loci highly
fluid/secretion
at STAGE
physiological period fetal
Text brain, lung, liver, kidney
PROTEIN
PHYSICAL PROPERTIES basic
STRUCTURE
motifs/domains
  • a helix-loop-helix motif
  • a basic region
    • HOMOLOGY
    interspecies homolog to C.elegans W05E10.2
    Homologene
    FAMILY
    CATEGORY DNA associated , protooncogene
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • having a functional role during normal fetal development
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS development
    text normal development and oncogenesis
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    Other expression coregulated with MYCN gene in tumor cell lines under basal growth conditions and in response to the differentiating agent retinoic acid
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS