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FLASH GENE
Symbol MYCNOS contributors: npt - updated : 29-04-2003
HGNC name v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) opposite strand
HGNC id 16911
DNA
TYPE functioning gene
SPECIAL FEATURE gene in gene, antisens
STRUCTURE 0.00 kb     1 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
text two polyadenylation sites and multiple 5-prime ends (Armstrong, 1992)
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines tumor cell lines containing amplified N-myc loci highly
fluid/secretion
at STAGE
physiological period fetal
Text brain, lung, liver, kidney
PROTEIN
PHYSICAL PROPERTIES basic
STRUCTURE
motifs/domains
  • a helix-loop-helix motif
  • a basic region
    • HOMOLOGY
    interspecies homolog to C.elegans W05E10.2
    Homologene
    FAMILY
    CATEGORY DNA associated , protooncogene
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • having a functional role during normal fetal development
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS development
    text normal development and oncogenesis
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    Other expression coregulated with MYCN gene in tumor cell lines under basal growth conditions and in response to the differentiating agent retinoic acid
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS