Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol TBL1Y contributors: mct - updated : 01-09-2020
HGNC name transducin (beta)-like 1Y-linked
HGNC id 18502
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a F-box-like domain
  • a LISH domain
  • eight WD repeats
    • HOMOLOGY
    intraspecies homolog to TBL1X
    Homologene
    FAMILY WD repeat EBI family
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • involved in signal transduction, RNA processing, gene regulation, vesicular trafficking
  • playing a role in the maleness
  • TBL1Y is involved in the genesis of non-syndromic coarctation of the aorta
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene could be considered a novel candidate for Hereditary hearing loss (HHL)
    Marker
    Therapy target
    ANIMAL & CELL MODELS