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FLASH GENE
Symbol SNX8 contributors: SGE/npt - updated : 18-01-2010
HGNC name sorting nexin 8
HGNC id 14972
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
11 - 1522 15.44 465 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
blood / hematopoieticspleen   highly
Cardiovascularheart   highly
Urinarykidney   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Lymphoid    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • one PX domain (phosphoinositide binding domain)
    • conjugated PhosphoP
    HOMOLOGY
    interspecies homolog to rattus Snx8 (89.5pc)
    homolog to murine Snx8 (89.5pc)
    Homologene
    FAMILY
  • sorting nexin family
    • CATEGORY signaling , transport
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,endosome
    basic FUNCTION
  • involved in several stage of intracellular trafficking
  • involved in endosomal sorting (Dyve 2009)
    • CELLULAR PROCESS cell communication
    PHYSIOLOGICAL PROCESS cellular trafficking transport
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS