Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | FCGR2A | contributors: mct - updated : 21-06-2017 |
HGNC name | Fc fragment of IgG, low affinity IIa, receptor (CD32) |
HGNC id | 3616 |
|
Location | 1q23.3 Physical location : 161.475.204 - 161.489.359 |
Synonym name | |
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Synonym symbol(s) | CD32, FCG2, FCG2A, FCR2, IGFR2, FCGR2A1, CD32A, CDw32, Fc-gamma-RIIa, MGC23887, MGC30032 |
DNA |
TYPE | functioning gene |
STRUCTURE | 14.16 kb 7 Exon(s) |
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Genomic sequence alignment details |
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10 Kb 5' upstream gene genomic sequence study |
MAPPING | cloned | Y | linked | N | status | confirmed |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type |
expressed in | (based on citations) | ||||||||||||||||||||
organ(s) |
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tissue |
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cells |
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cell lineage | primarily, by cells of the myeloid lineage |
cell lines | |
fluid/secretion |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES |
STRUCTURE |
motifs/domains
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|
mono polymer | hexamer |
HOMOLOGY |
Homologene |
FAMILY |
CATEGORY | antigen , receptor |
SUBCELLULAR LOCALIZATION
| plasma membrane |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein | ![]() |
cell & other |
REGULATION |
activated by | in platelets downstream G-protein-coupled receptors (may be a novel general mechanism for the reinforcement of platelet activation induced by low concentrations of agonists) (Canobbio 2006) |
ASSOCIATED DISORDERS |
corresponding disease(s) |
Susceptibility |
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Candidate gene |
Marker |
Therapy target |
ANIMAL & CELL MODELS |