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FLASH GENE
Symbol SLC26A11 contributors: np/ - updated : 15-11-2005
HGNC name solute carrier family 26, member 11
HGNC id 14471
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
made of a N and C cytoplasmic termini:
  • twelve transmembrane segments (12TM)
  • a large cytoplasmic tail
  • a sulfate transporter motif
  • a relatively hydrophobic region near the C terminus
  • the STAS domain (sulfate transporter and anti-sigma factor antagonist)
    • HOMOLOGY
    Homologene
    FAMILY
  • anion exchanger family
  • SLC26A/SulP transporter (TC 2.A.53) family
    • CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • anion exchanger, Na+ independent
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • SLC26A2 to mediate DIDs-sensitive sulfate uptake in HEVEC (high endothelial venuls, endothelial cells)
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS