| Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
|---|
| tumoral
|
|
| --over
|
|
in osteosarcoma tissues compared with that in adjacent normal ones, and may predict poor prognosis among osteosarcoma patients  |
| tumoral
|
|
| --over
|
|
|
in urothelial carcinoma is associated with features of aggressive tumor biology and portends a poor prognosis |
| tumoral
|
|
| --over
|
|
|
is highly overexpressed in malignant cells of acsites in gastric carcinoma |
| constitutional
|
|
| --low
|
|
|
reduced SLC16A4 and SLC1A3 expression by astrocytes may lead to neuronal hyperexcitability and epileptogenesis in the temporal lobe by reducing the supply of metabolic intermediates and by allowing accumulation of extracellular glutamate |
| tumoral
|
|
| --over
|
|
|
SLC16A44 and BSG overexpression correlated with higher PSA levels, as well as with perineural invasion and biochemical recurrence in prostate carcinoma |
