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FLASH GENE
Symbol SFXN2 contributors: - updated : 09-10-2007
HGNC name sideroflexin 2
HGNC id 16086
DNA
TYPE functioning gene
STRUCTURE 24.00 kb     12 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart    
Digestiveesophagus   moderately
 liver    
Endocrinepancreas    
 parathyroid   highly
 thyroid   moderately
Reproductivefemale systembreastmammary gland  
 male systemprostate   
Urinarykidney   predominantly
Visualeye    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Nervousperipherous   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • tricarboxylate/iron carrier motif
    • HOMOLOGY
    interspecies homolog to dog SFXN2 (94.4 pc)
    homolog to chimpanzee SFXN2 (99.7 pc)
    homolog to murine Sfxn2 (89.1 pc)
    homolog to chicken SFXN2 (74.7 pc)
    Homologene
    FAMILY
  • sideroflexin family
    • CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,inner
    basic FUNCTION
  • involved in iron ion transport
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    text
  • iron ion transport
    • PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • Fe2+
    • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS