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FLASH GENE
Symbol SDCBP2 contributors: np - updated : 03-01-2007
HGNC name syndecan binding protein (syntenin) 2
HGNC id 15756
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • two PDZ (PSD95,Dlg,Z0-1/2) motifs
    • mono polymer homomer , monomer , dimer
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     plasma membrane,junction,adherens
        intracellular
    intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
    intracellular,cytoplasm,cytosolic,microsome
    intracellular,cytoplasm,cytoskeleton,microfilament
    intracellular,nucleus
    basic FUNCTION
  • regulation of plasma membrane dynamics
  • potential role in nuclear processes
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • component of adherens junctions with syndecans 1,E-cadherin,beta and alpha-catenins
  • forming homodimers and heterodimers with SDCBP
    • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • associating with the cytoplasmic tail of ILR5R alpha
  • interacting with the FYA motif of syndecan
  • interacting with the cytoplasmic tail of neurofascin
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS