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FLASH GENE
Symbol SDCBP2 contributors: np - updated : 03-01-2007
HGNC name syndecan binding protein (syntenin) 2
HGNC id 15756
DNA
TYPE functioning gene
STRUCTURE 19.22 kb     9 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 1484 - 292 - -
9 - 1595 - 292 - -
5 - 1375 - 207 - -
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain   highly
cells
SystemCellPubmedSpeciesStageRna symbol
 epithelial cell
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • two PDZ (PSD95,Dlg,Z0-1/2) motifs
    • mono polymer homomer , monomer , dimer
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     plasma membrane,junction,adherens
        intracellular
    intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
    intracellular,cytoplasm,cytosolic,microsome
    intracellular,cytoplasm,cytoskeleton,microfilament
    intracellular,nucleus
    basic FUNCTION
  • regulation of plasma membrane dynamics
  • potential role in nuclear processes
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • component of adherens junctions with syndecans 1,E-cadherin,beta and alpha-catenins
  • forming homodimers and heterodimers with SDCBP
    • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • associating with the cytoplasmic tail of ILR5R alpha
  • interacting with the FYA motif of syndecan
  • interacting with the cytoplasmic tail of neurofascin
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS