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FLASH GENE

Symbol

CEACAM5

contributors: - updated : 01-07-2006

HGNC name	carcinoembryonic antigen-related cell adhesion molecule 5
HGNC id	1817

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
SPECIAL FEATURE	component of a cluster
STRUCTURE	21.00 kb     10 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

confirmed

Map

see CEA@

RNA

TRANSCRIPTS	type	messenger

EXPRESSION

Type

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive intestine large intestine colon       mouth tongue         stomach         Endocrine pancreas       moderately Respiratory lung       moderately   respiratory tract trachea

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Muscular striatum skeletal

cell lineage
cell lines	adenocarcinomas of endodermally derived digestive system epithelium and fetal colon
fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

seven immunoglobulin-like domains

conjugated

GlycoP

HOMOLOGY

intraspecies

homolog to carcinoembryonic antigen

Homologene

FAMILY	immunoglobulin superfamily
	CEA subfamily

CATEGORY

adhesion , antigen

SUBCELLULAR LOCALIZATION	plasma membrane
text	attached to the membrane by a GPI-anchor

basic FUNCTION

acting as a tumor antigen

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

complex immunoreactive glycoprotein of 180 kDa comprising 60% carbohydrate

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS