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FLASH GENE
Symbol RBM7 contributors: SGE/npt - updated : 22-07-2010
HGNC name RNA binding motif protein 7
HGNC id 9904
Location 11q23.2      Physical location : 114.271.383 - 114.279.632
Synonym symbol(s) FLJ11153
DNA
TYPE functioning gene
STRUCTURE 8.25 kb     5 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
5 - 2025 - 266 - Guo (2003)
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivemale systemtestis   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • one RRM domain
  • conjugated PhosphoP
    HOMOLOGY
    interspecies homolog to murine Rrm7 (83.8pc)
    homolog to rattus Rrm7 (83.4pc)
    Homologene
    FAMILY
    CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    text
  • ZCCHC8 and RBM7 are excluded from nucleoli
  • basic FUNCTION
  • may be a pre-mRNA splicing factor
  • may be involved in germ cell RNA processing and meiosis (Guo 2003)
  • CELLULAR PROCESS cell cycle,division,meiosis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component part of the trimeric Nuclear Exosome Targeting (NEXT) complex, containing SKIV2L2, the Zn-knuckle protein ZCCHC8, and the putative RNA binding protein RBM7
    INTERACTION
    DNA
    RNA binding
    small molecule
    protein
  • interacting with SF3B2 and SFRS3 (Guo 2003)
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS