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FLASH GENE
Symbol RBM7 contributors: SGE/npt - updated : 22-07-2010
HGNC name RNA binding motif protein 7
HGNC id 9904
Location 11q23.2      Physical location : 114.271.383 - 114.279.632
Synonym symbol(s) FLJ11153
DNA
TYPE functioning gene
STRUCTURE 8.25 kb     5 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
LOC387810 11 LOC387810 NCAM1 11q23.1 neural cell adhesion molecule 1 TTC12 11q23.2 tetratricopeptide repeat domain 12 ANKK1 11q23.2 ankyrin repeat and kinase domain containing 1 DRD2 11q23.1 dopamine receptor D2 TMPRSS5 11q23 transmembrane protease, serine 5 (spinesin) ZW10 11q22-q23.3 ZW10 homolog, centromere/kinetochore protein (Drosophila) LOC255244 11q23.3 similar to Claudin-22 LOC390251 11 hypothetical gene supported by AK093353 LOC143920 11q23.3 similar to activating transcription factor 4; cAMP response element-binding protein 2 USP28 11q23 ubiquitin specific protease 28 HTR3B 11q23.1-q23.2 5-hydroxytryptamine (serotonin) receptor 3B HTR3A 11q23.1-q23.2 5-hydroxytryptamine (serotonin) receptor 3A ZNF145 11q23.1 zinc finger protein 145 (Kruppel-like, expressed in promyelocytic leukemia) NNMT 11q23.1 nicotinamide N-methyltransferase FLJ20010 11q14.2-q14.3 hypothetical protein FLJ20010 RBM7 11q23.1-q23.2 RNA binding motif protein 7 DKFZP566E144 11q23.1-q23.2 small fragment nuclease MGC34290 11q23.3 hypothetical protein MGC34290 C11orf33 11q23.3 chromosome 11 open reading frame 33 LOC390252 11 similar to putative protein family member (XC187) LOC390253 11 similar to putative protein family member (XC187) FLJ25224 11q23.3 hypothetical protein FLJ25224 IGSF4 11q23.2 immunoglobulin superfamily, member 4 LOC387811 11 similar to hypothetical protein FLJ25224
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
5 - 2025 - 266 - Guo (2003)
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivemale systemtestis   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • one RRM domain
  • conjugated PhosphoP
    HOMOLOGY
    interspecies homolog to murine Rrm7 (83.8pc)
    homolog to rattus Rrm7 (83.4pc)
    Homologene
    FAMILY
    CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    text
  • ZCCHC8 and RBM7 are excluded from nucleoli
  • basic FUNCTION
  • may be a pre-mRNA splicing factor
  • may be involved in germ cell RNA processing and meiosis (Guo 2003)
  • CELLULAR PROCESS cell cycle,division,meiosis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component part of the trimeric Nuclear Exosome Targeting (NEXT) complex, containing SKIV2L2, the Zn-knuckle protein ZCCHC8, and the putative RNA binding protein RBM7
    INTERACTION
    DNA
    RNA binding
    small molecule
    protein
  • interacting with SF3B2 and SFRS3 (Guo 2003)
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS