Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

PRDM16

contributors: mct/ - updated : 18-04-2017

HGNC name	PR domain containing 16
HGNC id	14000

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

LVNC8

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral fusion       fusion with RUNX1 in a patient with acute myeloid leukemia showing t(1;21)(p36;q22) tumoral     --over   in the t(1;3)(p36;q21)-positive MDS/AML cell lines tumoral     --other   aberrant gene expression associated with DNA hypomethylation is implicated in leukemogenesis of adult T-cell leukemia constitutional     --other   ectopic exression in myoblasts induces their differentiation into brown fat cells

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed obesity     inducing the expression of PRDM16 in white fat or muscle progenitors could be powerful in fighting obesity

ANIMAL & CELL MODELS