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FLASH GENE

Symbol

PRRX1

contributors: mct - updated : 22-08-2012

HGNC name	paired related homeobox 1
HGNC id	9142

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	loss of function mutation in the mouse Pmx1 gene
	Homozygous for the mutant allele died soon after birth and exhibited defects of skeletogenesis
	mice lacking Prrx1 die postnatally and have impaired formation of osteogenic and chondrogenic progenitors, resulting in defective skeletogenesis