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FLASH GENE

Symbol

OXCT2

contributors: - updated : 27-09-2004

HGNC name	3-oxoacid CoA transferase 2
HGNC id	18606

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
SPECIAL FEATURE	gene in gene
text	located in an intron of BMP8
STRUCTURE	1.00 kb     1 Exon(s)

Genomic sequence alignment details
10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

Map	Pter - BMP8B - OXCT2 OXCT2 - PPIE - HPCAL4 - HEYL - PABPC4 - BMP8A - MACF1 - OXCT2P - Cen
Authors	Onishi (2004)

RNA

TRANSCRIPTS	type	messenger

EXPRESSION

Type	restricted

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Reproductive male system testis

cells

System Cell Pubmed Species Stage Rna symbol Reproductive spermatozoa

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

mono polymer

homomer , dimer

HOMOLOGY

interspecies

ortholog to murine Scot-t

Homologene

FAMILY

3-oxoacidCoA-transferase family

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,organelle,mitochondria,matrix

basic FUNCTION

key enzyme for ketone body catabolism, transfering the CoA moiety from succinate to acetoacetate

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

energetic

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

corresponding disease(s)

OXCT2

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS