Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol OXCT2 contributors: - updated : 27-09-2004
HGNC name 3-oxoacid CoA transferase 2
HGNC id 18606
Corresponding disease
OXCT2 succinyl-CoA ketoacid CoA-transferase
Location 1p34.3      Physical location : 40.235.196 - 40.237.020
Synonym symbol(s) FKSG25, SCOT-T, FLJ00030
EC.number 2.8.3.5
DNA
TYPE functioning gene
SPECIAL FEATURE gene in gene
text located in an intron of BMP8
STRUCTURE 1.00 kb     1 Exon(s)
Genomic sequence alignment details
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Map Pter - BMP8B - OXCT2 OXCT2 - PPIE - HPCAL4 - HEYL - PABPC4 - BMP8A - MACF1 - OXCT2P - Cen
Authors Onishi (2004)
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivemale systemtestis   
cells
SystemCellPubmedSpeciesStageRna symbol
Reproductivespermatozoa
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer homomer , dimer
HOMOLOGY
interspecies ortholog to murine Scot-t
Homologene
FAMILY 3-oxoacidCoA-transferase family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,mitochondria,matrix
basic FUNCTION
  • key enzyme for ketone body catabolism, transfering the CoA moiety from succinate to acetoacetate
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism energetic
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) OXCT2
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS