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FLASH GENE
Symbol APOC4 contributors: - updated : 31-05-2006
HGNC name apolipoprotein C-IV
HGNC id 611
Location 19q13.2      Physical location : 45.445.494 - 45.448.751
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
text APO-C cluster
STRUCTURE 3.00 kb     3 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status confirmed
regionally located located 0.5 kb 5' to the APOC2 gene
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver   predominantly
Respiratorylung   lowly
cells
SystemCellPubmedSpeciesStageRna symbol
Digestivehepatocyte
cell lineage
cell lines
fluid/secretion plasma
at STAGE
PROTEIN
PHYSICAL PROPERTIES Amphiphilic
STRUCTURE
motifs/domains
  • a 25 AA signal peptide
  • two potential amphipathic alpha helix domains
    • conjugated GlycoP
    HOMOLOGY
    interspecies ortholog to murine Apoc4
    Homologene
    FAMILY apolipoprotein family
    CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION participating in lipoprotein metabolism
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    text lipid transport
    PATHWAY
    metabolism lipid/lipoprotein
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS