basic FUNCTION
| playing a role in the nuclear export of U1 snRNA, tRNA, |
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and mRNA |
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NXF1/NXT1 heterodimer enhances nucleoporin binding and induces the formation of a NXF1/NXT1/nucleoporin ternary complex, a key intermediate in the process of nuclear mRNA export |
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may act as a molecular switch that regulates the ability of NXF1 to mediate nuclear mRNA export by controlling the interaction of NXF1 with components of the nuclear pore |
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nuclear export of mRNAs is mediated by the NXF1/NXT1 pathway |
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role for this gene in tissue specific transcription |
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NXF2 and its co-factor, NXT1, form a complex with PANX and are required for co-transcriptional silencing of transposons in somatic and germline cells of the ovary |