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Symbol NUDT11 contributors: mct - updated : 24-12-2014
HGNC name nudix (nucleoside diphosphate linked moiety X)-type motif 11
HGNC id 18011
Location Xp11.22      Physical location : 51.232.871 - 51.239.459
Synonym name
  • nudix motif 11
  • DIPP3 beta
  • diphosphoinositol polyphosphate phosphohydrolase 3 beta
  • Synonym symbol(s) DIPP3b, FLJ10628, hDIPP3beta, ASP1, DIPP3beta, hDIPP3beta, APS1
    EC.number 3.6.1.52/ 3.6.1.60
    DNA
    TYPE functioning gene
    SPECIAL FEATURE arranged in tandem
    text arranged in tadem with NUDT10
    STRUCTURE 6.60 kb     2 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    2 - 2413 - 164 - 2002 12121577
    EXPRESSION
    Type restricted
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousbrain   specific Homo sapiens
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    Nudt (MutT) motif
    HOMOLOGY
    interspecies ortholog to mouse Nudt11
    intraspecies paralog to NUDT10
    Homologene
    FAMILY
  • NUDIX family of hydrolases
  • DIPP subfamily
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic
    basic FUNCTION
  • hydrolase activity
  • acting as an intracellular messenger
  • is a diphosphoinositol polyphosphate phosphohydrolase
  • NUDT11, SLC22A3, HNF1B contribute to prostate cancer pathogenesis
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • Mg2+
  • Mn2+
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS