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FLASH GENE

Symbol

NEK9

contributors: mct/pgu - updated : 01-06-2016

HGNC name	NIMA (never in mitosis gene a)- related kinase 9
HGNC id	18591

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

LCCSR

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   overexpressed in primary breast tumors constitutional somatic mutation       in NC (Nevus Comedonicus) disrupt normal follicular differentiation

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer     NEK9 inhibition represents a novel anti-cancer strategy by induction of mitotic catastrophe via impairment of spindle dynamics, cytokinesis and mitotic checkpoint control

ANIMAL & CELL MODELS