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FLASH GENE

Symbol

NDUFB4

contributors: npt - updated : 05-11-2009

HGNC name	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa
HGNC id	7699

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
STRUCTURE	6.05 kb     3 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_004547 3 - 541 NP_004538 - 129 - -

EXPRESSION

Type	ubiquitous

constitutive of

expressed in	(based on citations)
organ(s)

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Blood / Hematopoietic bone marrow       Muscular striatum skeletal

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES		Hydrophilic Hydrophobic
STRUCTURE

motifs/domains

conjugated

Other

mono polymer

heteromer , complex

HOMOLOGY

interspecies

homolog to C.elegans R06A10.1

Homologene

FAMILY

complex I NDUFB4 subunit family

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,organelle,mitochondria,inner

basic FUNCTION	transfert of electrons from NADH to the respiratory chain
	NADH dehydrogenase activity

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

energetic

signaling

a component

one of the forty one subunits of the respiratory complex,in its hydrophobic protein chain fraction

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS