Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol KCNG3 contributors: mct - updated : 24-06-2014
HGNC name potassium voltage-gated channel, subfamily G, member 3
HGNC id 18306
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a N terminal cytoplasmic domain
  • six transmembrane domains,the fourth being probably the voltage sensor
  • a pore forming domain between the fifth and sixth transmembrane domains
    • mono polymer heteromer , tetramer
    HOMOLOGY
    interspecies homolog to rattus Kcng3
    Homologene
    FAMILY
  • potassium channel family, G subfamily
    • CATEGORY regulatory , transport channel
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
    basic FUNCTION
  • potassium channel subunit modulating channel activity
  • mediating the voltage-dependent potassium ion permeability of excitable membranes.
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS facilitated diffusion transport
    PATHWAY
    metabolism
    signaling
    a component
  • forming potassium channels only if heteromultimerized
  • KCNB1 or KCNC1 or KCNF1
    • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    activated by BMP2 that significantly (>2-fold) upregulated mRNA expression of KCNG3
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS