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FLASH GENE
Symbol MRPL23 contributors: - updated : 24-05-2006
HGNC name mitochondrial ribosomal protein L23
HGNC id 10322
Location 11p15.5      Physical location : 1.968.501 - 1.977.837
Synonym name L23 mitochondrial related protein
Synonym symbol(s) L23mrp, RPL23, RPL23L
DNA
TYPE functioning gene
SPECIAL FEATURE opposite orientation, tail to tail
text oriented tail to tail with H19
STRUCTURE 9.00 kb     5 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
regionally located located 40kb of the last H19 exon
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart    
Digestiveintestinelarge intestine  highly
Endocrineneuroendocrinepituitary  highly
 pancreas    
Lymphoid/Immunetonsils   highly
Reproductivefemale systemuterus  highly
Respiratorylung    
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
cell lineage
cell lines in Wilms tumors
fluid/secretion
at STAGE
physiological period fetal, pregnancy
Text tissues and placenta
IMPRINTING
text
  • not imprinted in humans
    • PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    interspecies homolog to yeast mitochondrial ribosomal protein 20 (isolated from the IGF2/H19 imprinted domain)
    Homologene
    FAMILY
    CATEGORY structural protein , RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,matrix
    text mitochondrial ribosome
    basic FUNCTION
  • mitochondrial proteins biosynthesis
  • ribosomal structure and biogenesis
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component component of the large subunit (39S) of the mitochondrial ribosome, including two RNA molecules and, at least, 70 proteins among which 47 proteins for the large subunit
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS