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FLASH GENE

Symbol

HIF1AN

contributors: mct - updated : 08-09-2012

HGNC name	hypoxia-inducible factor 1, alpha subunit inhibitor
HGNC id	17113

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral         silencing of HIF1AN significantly increased both the total and phosphorylated forms of the tumor suppressor TP53, leading to an increase in its direct target CDKN1A tumoral     --other   expressed in the majority of invasive breast carcinomas and shows distinct subcellular localization patterns

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS