basic FUNCTION
| involved in the mobilization of calcium |
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stimulation of phosphoinositide turnover |
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activation of p44/p42 MAPK signaling pathways consistent with the effects of prokineticins on smooth muscle contraction and angiogenesis |
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not necessary for suprachiasmatic nucleus cellular timekeeping or entrainment, but it is an essential link for coordination of circadian behavior and physiology by the suprachiasmatic nucleus, especially in defining the onset and maintenance of circadian night |
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mediating circadian control of behavior rather than circadian timing per se |
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having a dimeric structure in neutrophils (pMID: 21161321) |
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PROKR1, but also PROKR2 might mediate a complementary signalling to the RET/GDNF pathway supporting proliferation/survival and differentiation of precursor cells during enteric nervous system (ENS) development |
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undergoes rapid ligand-induced endocytosis, and recycles back to the plasma membrane after the removal of ligand |
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involved in the regulation of sexual maturation |