| basic FUNCTION
| acting as a presynaptic organizer |
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ligand of FGFR2, involved in presynaptic differentiation of mossy fibers |
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may be playing a role in hair development |
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FGF22 and SIRPA induced vesicle clusters of different sizes, differed in their ability to promote neurite branching, and acted through different receptors and signaling pathways  |
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FGF22 and FGF7, promote the organization of excitatory and inhibitory presynaptic terminals, respectively, as target-derived presynaptic organizers |
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FGF22, FGF7 act as target-derived presynaptic organizers and help to organize specific presynaptic terminals in the mammalian brain |
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FGF22 is an important "organizing" cue for the timely development of retinogeniculate synapses |
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have a clear role in synaptogenesis, but also a potential pro-oncogenic role in the skin |
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plays important roles in controlling neurogenesis, ectopic migration of dentate granule cells (DGCs), and hilar cell death after seizures, which may contribute to the generalized seizure-resistant phenotype of FGF22KO mice |
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potentially involved in midbrain development downstream of FGF3 and FGF8 in the midbrain-hindbrain boundary (MHB) but not of Hh in the floor plate |
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FGF22 and FGF7 are postsynaptic-cell-derived presynaptic organizers necessary for excitatory and inhibitory presynaptic differentiation, respectively, in the hippocampus |
